With extensive experience in isolating and culturing primary cells from various tissues and organs, Creative Bioarray can provide a wide range of primary cells to be used as more biologically relevant tools in your research. We can offer customized services upon the requests of our customers.
About Primary Cells
Primary cells refers to the cells that are directly isolated from living tissues. They can be cultured in an artificial environment and established for growth in vitro. Primary cells can be isolated from most tissues and organs, such as brain, colon, bone, blood vessel, heart, epithelium, connective tissue, muscle tissue and nervous tissue. However, there are differences in growth rate, isolation method and culture difficulty among different primary cells.
Compared with the continuous cell lines, primary cells are most closely to the tissue of origin, thus are more representative models to the in vivo state. However, they have limited life span and are more difficult to culture in vitro.
Applications of Primary Cells
Primary cells can retain normal morphology, growth characteristics, cellular markers, functions, and genetic integrity. Therefore, they are widely used in molecular biology, cell biology and biomedical basic research, such as proteomics, genomics, cell research, and genetic research. Not only that, they are also ideal cell models used in biopharmaceutics, such as the study of disease mechanisms, drug screening, drug metabolism, toxicology research, cancer drug research, and therapeutic development.
Primary cells can provide excellent models to study the effects of drugs and toxic compounds. Primary cells from different species can be used to varify the potential differences between species used in preclinical trials and the accuracy of extrapolating human data from animal models.
Primary Cell Isolation Services
The methods used to isolate primary cells mainly include mechanical isolation, enzyme digestion, magnetic isolation and density gradient separation. We have extensive experience in isolating primary cells from multiple tissues using appropriate methods. We can isolate the desired cell type and prepare ready-to-use cells with low passage number for our customers. The isolated primary cells will be fully tested and authenticated to ensure purity.
We have successfully isolated primary cells from multiple species, such as human, bovine, chicken, dog, hamster, horse, monkey, mouse, porcine, rabbit, rat and some other animals.
